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Keywords: Radiobiology
MO-AB-KDBRA1-6Mapping Biological Effects Along a Scanned 81.4 MeV Proton Beam: LET Modulation of the DNA Repair Response
L Bronk*, B Kroger , D Ma , M Kerr , K Tran , F Teubner , D Patel , U Titt , N Sahoo , E Sulman , F Guan , R Mohan , D Grosshans , The University of Texas MD Anderson Cancer Center, Houston, TX
MO-K-DBRA-5Incorporating a Novel Radiomics Framework for Biologically Optimised Prostate RadioTherapy (BiRT)
A Haworth1*, Y Sun2 , M Ebert3 , H Reynolds4 , J Betts5 , D Wraith6 , C Mitchell7 , D Murphy8 , S Williams9 , (1) University of Sydney, Sydney, New South Wales, (2) University of Sydney, Sydney, New South Wales, (3) The University of Western Australia, Nedlands, ,(4) Peter MacCallum Cancer Centre, Melbourne, Victoria, (5) Monash University, Clayton, Vic, (6) Queensland University of Technology, Kelvin Grove, Qld, (7) Peter MacCallum Cancer Centre, Parkville, Vic, (8) Peter MacCallum Cancer Centre, Parkville, Vic, (9) Peter MacCallum Cancer Centre, Melbourne, Victoria
SU-F-DBRA-1Development of a TEM Image-Based Cellular Geometry Model for Geant4 Monte Carlo Simulations of GNP-Mediated Dose Enhancement/radiosensitization
S Jayarathna*, S Krishnan , S H Cho , The University of Texas MD Anderson Cancer Center, Houston, TX
SU-F-KDBRA1-2Biological Comparison of Targeted Marrow Irradiation and Total Body Irradiation by the Generalized Equivalent Uniform Dose (gEUD)
G Warrell*, V Colussi , W Swanson , D Mansur , G Pereira , University Hospitals Cleveland Medical Center, Cleveland, OH
SU-I-GPD-SPS-2Identification of DNA Repair Variants in Ancestral Populations That May Impact Normal Tissue Radiosensitivity
T Edwards*, L Ricks-Santi , J McDonald , Hampton University, Hampton, Virginia
SU-I-GPD-T-79Generating Fetal Doses for Pregnant Survivors of the Atomic Bombs in Hiroshima and Nagasaki
C Paulbeck*, W Bolch , university Florida, Gainesville, FL
SU-I-GPD-T-457Clonogenic Assay of Normal Cell Lines Treated by Pulsed Low-Dose-Rate Radiotherapy
J Xu1*, Y Zhang1,2 , C Ma1 , (1) Fox Chase Cancer Center, Philadelphia, PA, USA, (2) Tangdu Hospital, Air Force Military Medical University, Xi'an, Shaanxi, China
SU-I-GPD-T-459A Computational-Experimental Approach to Predict the Response of Glioma Cells to Radiotherapy
J Liu1*, D Hormuth2 , M Mckenna6 , T Davis1 , T Yankeelov1-6 , (1) Biomedical Engineering, The University of Texas at Austin, (2) Institute for Computational Engineering and Science, The University of Texas at Austin, (3) Diagnostic Medicine, The University of Texas at Austin, (4) Oncology, The University of Texas at Austin, (5) Livestrong Cancer Institutes, The University of Texas at Austin , (6)Department of Biomedical Engineering, Vanderbilt University
SU-I-GPD-T-461Measurement of Radiation-Induced Injury in Mouse Brain by Magnetic Resonance Imaging and Histology
A Boria*, C Perez-Torres , Purdue University, West Lafayette, IN
SU-I-GPD-T-462Effect of Reoxygenation On Hypofractionated Treatment: A Theoretical Comparison with the Linear-Quadratic Model
HHF Choi*, PH Nam , KY Cheung , SK Yu , Hong Kong Sanatorium & Hospital, Hong Kong, Hong Kong
SU-I-GPD-T-463Modeling of Radiation Damage of Various Plasmid Loop Conformations
M Sefl1,2*, K Stefanova2 , K Pachnerova Brabcova1 , V Stepan1 , (1) Nuclear Physics Institute of the Czech Academy of Sciences, Prague, (2) Czech Technical University in Prague, Prague
SU-I-GPD-T-466Immunologicalaspects of Improved Tumor and Normal Tissue Responses Using Biophysicalmodelling
M Oita1*, M Udaka1 , H Aoyama2 , M Sasaki3 , M Tominaga4 , Y Uto5 , (1) Department of Radiological Technology, Graduate School of Health Sciences, Okayama University, (2) Department of Radiology, Okayama University Hospital, (3) Department of Radiological Technology, Institute of Health Biosciences, Graduate School,Tokushima University Hospital, (4) The Tokushima University, (5) Department of Life SystemTo, Institute of Technology and Science, Graduate School, The Tokushima University
SU-I-GPD-T-467Effect of Hypoxic Volume On Tumor Control Probability in Hypoxia Targeted Dose Escalation
A Chvetsov*, J Rajendran , J Zeng , University of Washington School of Medicine, Seattle, WA
SU-J400-CAMPUS-F3-2Monte Carlo Track Structure Simulations of Radiation Induced Damage in a Fractal Globule Full Nuclear DNA Model
A McNamara1*, J Ramos-Mendez2 , J Perl3 , B Faddegon2 , H Paganetti1 , J Schuemann1 , (1) Massachusetts General Hospital & Harvard Med. Sch., Boston, MA, (2) University of California San Francisco, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, (3) SLAC National Accelerator Laboratory, Menlo Park, CA.
SU-K-DBRA-5Increased Carcinoembryonic Antigen Expression On the Surface of Lung Cancer Cells During Radiotherapy
R Mueller1,2,3*, S Yasmin-Karim3,4 , J Hesser1,2,5,6 , W Ngwa3,4,7 (1) University Medical Center Mannheim, Mannheim, Germany, (2) Heidelberg University, Heidelberg, Germany, (3) Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, MA, (4) Harvard Medical School, Boston, MA, (5) Interdisciplinary Center for Scientific Computing (IWR), Heidelberg, Germany (6) Central Institute for Computer Engineering (ZITI), Mannheim, Germany, (7) University of Massachusetts Lowell, Lowell, MA
TH-EF-KDBRB1-11MR-Only Planning for Simultaneous Integrated Boost of Multi-Modal MRI-Defined Dominant Intraprostatic Lesions
M Leney1*, J Kim2 , C Liu2 , P Sevak2, C Glide-Hurst2 , D Hearshen2 , M Elshaikh2 , M Pantelic2, B Movsas2 , I Chetty2 , N Wen2 , (1) Karmanos Cancer Center at McLaren Macomb Hospital, Mount Clemons, MI, (2) Henry Ford Health System, Detroit, MI
TU-C930-GePD-F4-2Investigation Into the Effects of Radiation Spatial-Fractionation Pattern On Treatment Response in a Rat Tumor Model
JN Rivera1,2*, SK Kasoji1,2 , TM Kierski1,2 , PA Dayton1,2 , SX Chang1,3 , (1) (2) University of North Carolina, Chapel Hill, NC, (2) NC State University, Raleigh, NC (3) UNC School of Medicine, Chapel Hill, NC
TU-GH-KDBRA1-7The Importance of DNA Double Strand Break Repair Defects to Cell Radiosensitivity in Helium and Carbon Ion Beams
D Flint1 , C Mcfadden1 , S Bright1 , D Yoon1 , S Kodaira2 , T Konishi2 , G Sawakuchi1*, (1) MD Anderson Cancer Center, Houston, Texas, USA; (2) National Institute of Radiological Sciences, Chiba, Japan
WE-C1000-GePD-F4-2Assessment of Hypofractionated High Dose-Rate Brachytherapy for Cervical Cancerusing Radiobiology-Based Treatment Planning
K Seeley1,2, I Hsu1 , T Hong2 , J A Cunha1*,(1) UC San Francisco, San Francisco, CA, (2) University of Pittsburgh, Pittsburgh, Pennsylvania