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Multi-Energy and Multi-Contrast CT Imaging

D Sahani1*, L Yu2*, K Taguchi3*, D Cormode4*, (1) Lexington, MA, (2) Mayo Clinic, Rochester, MN, (3) Johns Hopkins University, Baltimore, MD, (4) University of Pennsylvania, Philadelphia, PA


(Wednesday, 8/1/2018) 1:45 PM - 3:45 PM

Room: Room 202

Given its material differentiation and quantification capability, dual energy CT has provided a wide range of clinical applications such as bone removal, renal stone quantification, gout detection, virtual non-contrast imaging, plaque removal, and perfused blood volume imaging. A number of techniques have been implemented by CT vendors to acquire dual energy CT data. For most hospitals, dual energy CT has been a powerful tool to provide advanced imaging and enhanced patient care. Recently, multi-energy CT with more than two energies has been investigated by multiple researchers with the motivation to improve the performance of conventional dual energy CT or to generate novel clinical applications. Different technologies have been investigated, such as using the multi-sources and multi-filters or using emerging photon counting detector technology. Promising results from phantom, animal and patient studies have been recently reported by multiple groups using multi-energy CT. In addition, the advance of multi-energy CT also motivates the development of novel contrast agents which may push the envelope of CT beyond the conventional anatomic imaging. However, substantial challenges still exist with these technologies at current stage. Extensive ongoing and future research is needed to bring multi-energy, multi-contrast imaging into routine clinical practice. In this symposium, we invited 4 experts who have extensive experience in multi-energy CT to summarize the state of the art knowledge gained from the research in recent years, review the current challenges and potential solutions, and share their perspectives of future directions.

Learning Objectives:
1. Review principles, technical implementations, and clinical applications of dual energy CT
2. Learn techniques to multi-energy CT using conventional energy integrating detectors
3. Understand principles of photon-counting-detector based multi-energy CT, benefits, technical challenges and potential clinical applications
4. Discuss development of novel contrast agents and their applications using multi-energy CT

Funding Support, Disclosures, and Conflict of Interest: David Cormode: research grant from Philips.



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