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Designing a System for in Vivo XRF Measurement of Heavy Elements in Knee Bone

A Nobakht1*, R Faghihi1,2 , S sina1,2 , (1) Nuclear engineering department, Shiraz University, Shiraz, Iran (2) Radiation Research Center, Shiraz University, Shiraz, Iran


(Sunday, 7/29/2018) 4:00 PM - 4:30 PM

Room: Exhibit Hall | Forum 9

Purpose: X-ray fluorescence spectroscopy using the radioisotopes is commonly used to measure the accumulation of lead in human bones. The aim of this study is to design a XRF system for in-vivo measurement of heavy elements in knee using X-ray source using MCNP Monte Carlo simulations.

Methods: An X-ray source, the knee bone, and a HPGe detector was simulated in this study. Different concentrations of lead was simulated in bone. The optimal geometry set up of the detector to give the best counting results was then obtained. The x-ray source with all its components, was considered with different angles

Results: The results indicate that the 45 degree geometry (between the source, and the detector) is the optimum geometry for determining the percentage of lead in bone.

Conclusion: The advantage of using X-ray sources instead of radio-isotopic sources, is the measurement accuracy and speed. Due to the low half-life of common radio-isotopic sources, the clinical use of these types of sources is not cost-effective.


X Rays, K X-ray Fluorescence (KXRF)


IM- X-ray: Theory

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