(Saturday, 4/7/2018)
Room: Foyer
Purpose: The aim of this project is to develop a user-friendly GUI to calculate the applicator displacement and accelerate the process of calculation and evaluation of the EUD and EUD-based NTCP for organs at risk in High-Dose-Rate (HDR) Brachytherapy.
Methods: A Graphical User Interface (GUI) was created using MATLAB to calculate applicator displacement and radiobiological parameters in HDR Brachytherapy. To calculate the applicator displacement, the coordinates were extracted using CERR and then 3D point-cloud rigid registration method was applied to register two PTVs of interest from different fractions. Finally, translation and Euler angles were calculated to find the displacement of the applicators. Niemierko's EUD-based NTCP mathematical model was also implemented in the GUI for easy evaluation of EUD and NTCP for organs at risk in HDR Brachytherapy.
Results: Applicator displacements were successfully calculated and expressed in terms of rotation angles and translation if available. Radiobiological Parameters such as EUD and NTCP were also calculated in a fast and user friendly interface.
Conclusion: We implemented our unique method in the GUI to calculate the applicator displacements. Niemierko's EUD-based NTCP mathematical model was also implemented to calculate EUD and NTCP. The interface doesn’t require repeated command line inputs which reduces the user errors significantly and hence it is a very friendly tool for users without programing background.
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