Room: ePoster Forums
Purpose: The main aim of the study was to investigate the dosimetric difference of planning target volume (PTV) between Acuros XB algorithm(AXB), anisotropic analytic algorithm (AAA) and pencil beam convolution algorithmï¼ˆPBCï¼‰in stereotactic body radiation therapy (SBRT) planning for non-small cell lung cancer (NSCLC).
Methods: A compute tomography (CT) dataset of sixty-eight patients presenting with advanced non-small-cell lung cancer was selected, the tumor gross volume (GTV) was delineated by the radiation oncologists, planning target volume (PTV) was gained by the expanding of GTV, organs on risk of lungs, heart, and spinal cord were countered by the radiation oncologists. SBRT plans were initially created with AXB, then keeping identical optimization parameters, all plans of the same patients were also recalculated using AAA and PBC with the identical optimization parameters. The dosimetric difference of PTV between three different algorithms were compared
Results: For the V100%, AXB algorithm was minimum and PBC was maximum. The differences of V100% between PBC and AXB or AAA algorithm were statistically significant(P<0.05);The Dmin of PTV of AXB algorithm was minimum and PBC algorithm was maximum, the difference between the three algorithms were statistical significant differently(P<0.05); The Dmax of PTV of AAA was minimum and PBC was maximum; The Dmean of PTV of PBC algorithm was maximum, statistical difference for the Dmean of PTV were significant between PBC and AAA or AXB ( P<0.05).The CI in the group of PBC was minimum. The HI in AXB group was maximum.
Conclusion: For SBRT planning of non-small cell lung cancer, compared with the AXB algorithm, the PTV dose of the AAA algorithm is greater without statistical significance, the Eclipse PBC would underestimate the PTV dose significantly. AAA and PBC algorithms are inaccurate in SBRT calculation, and AXB algorithm can improve the accuracy of SBRT dose calculation.