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Organ Segmentation From CT Images Using Super Perception Convolutional Neural Networks for Cervical Cancer Brachytherapy

Z Zhang1*, S Wang1, Y He2, R Zhou1, Z Jin1, P Xie2, J Wei2, (1) Xiangya Hospital Central South of University, Changsha, Hunan,CN, (2) Perception Vision Medical Technology, Guangzhou, Guangdong,CN,


(Sunday, 7/12/2020)   [Eastern Time (GMT-4)]

Room: AAPM ePoster Library

Purpose: existence of applicator makes the organ segmentation very difficult on brachytherapy CT images. To address this issue, we developed a novel deep learning model to accuratly segment organs at risk from brachytherapy CT images.

Methods: developed a novel super perception convolutional neural network (SPNet) for organ segmentation from cervical cancer brachytherapy CT images. SPNet is constructed based on a classical pyramidal structure, with the double convolution block replaced by a super perception (SP) block, that combines the dilation convolution and inception convolution. The SPNet with a same scale has over four times perception filed than a general pyramidal network, such as the UNet. We collected 90 CT images of 90 cervical cancer patients treated by brachytherapy from our institution to test the segmentation tool. Three OARs: bladder, rectum and sigmoid with manually delineated, contours were checked for quality assurance by radiotherapy oncologist, and used as the ground truth. The proposed SPNet was trained using randomly selected 58 patients, internally validated on 10 patients and tested on the rest of the 22 patients. The segmentation accuracy is quantitatively evaluated by the Dice similarity coefficient. and compared with segmentation results from a UNet implementation.

Results: proposed method achieved a Dice value of 91.4(±2.0)%, 82.4(±6.0)% and 75.4(±8.9)% for bladder, rectum and sigmoid, respectively. For comparison, the Unet achieved a Dice value of 75.1(±16.1)%, 62.6(±16.6)% and 56.3(±17.8)%, respectively. As illustrate in Figure1, which shows the segmentation result of one test case, the contours predicted by proposed method match better with ground truth than those obtained from the UNet model.

Conclusion: quantitative and qualitive evaluation results demonstrate the proposed method is accurate in OARs segmentation for cervical cancer brachytherapy, and also demonstrate that our model outperforms the general pelvic OARs segmentation model.

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IM- CT: Machine learning, computer vision

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