Room: Track 5
Dual energy computed tomography (DECT) has a number of applications in radiotherapy and advantages over conventional single energy CT. In proton therapy, a source of uncertainty is the Hounsfield unit (HU) to proton stopping power ratio (SPR) relative to water conversion, which can be reduced through the use of DECT. The clinical implementation of DECT images for proton dose calculation will be presented as well as methods of experimental validation. The creation and employment of virtual non-contrast CT images will also be discussed.
The additional information gained through DECT also has potential to aid in several aspects of the radiation therapy process. We will highlight some of these applications, demonstrating areas where DECT has been used to improve target delineation, in areas such as the pancreas and liver. Moreover, we will discuss how DECT can aid in both tumor characterization as well as treatment response assessment. Finally, we will review the role of functional normal tissue segmentation in the radiation therapy process and discuss our experiences using DECT for this purpose.
1. Uncertainties in proton dose calculation due to conversion of HU to proton stopping power ratio (SPR) and how DECT can reduce range uncertainty
2. The use of DECT to calculate Zeff, electron density, SPR and the impact of contrast media
3. Improving tumor delineation and treatment response assessment using DECT
4. Use of DECT for functional tissue segmentation
Funding Support, Disclosures, and Conflict of Interest: Dr. Teo received research funds from Varian. Dr. Miller received research funds from Siemens Healthineers.
Dual-energy Imaging, Protons, Tissue Composition