Liver directed 90Y-microsphere therapies is firmly established as a loco-regional treatment option for the management of patients with both primary and metastatic liver cancers. The recent surge in enthusiasm is driven primarily by advances in the tailoring of patient-specific treatment dosimetry. This presentation will review the clinical indications for 90Y-microsphere therapies. The various methodology available for absorbed dose calculation related to Y90-microsphere SIRT will be presented. The importance of imaging for both treatment planning and verification will be discussed. Finally, approved commercial software packages available for Y90-SIRT dosimetry will be introduced.
Learning Objectives:
1. Identify clinical indications for 90Y-microsphere therapies.
2. Describe the different dosimetry methodologies for 90Y-microsphere therapies.
3. Describe the clinically available dosimetry software packages for 90Y-microsphere therapies.
Funding Support, Disclosures, and Conflict of Interest: Research Grants: Boston Scientific BTG, ABK Biomedical Consultant: Boston Scientific BTG, ABK Biomedical, Terumo Medical, Sirtex, Varian Medical