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ORBIT-RT: A Real-Time, Open Platform for Knowledge-Based Quality Control of Radiotherapy Treatment Planning

B Covele*, K Puri, K Kallis, K Moore, UC San Diego, La Jolla, CA


(Sunday, 7/12/2020)   [Eastern Time (GMT-4)]

Room: AAPM ePoster Library

Access to knowledge-based treatment plan quality control has been hindered by the complexity of developing models and differences between treatment planning systems (TPS). ORBIT-RT ( provides a free, web-based platform for knowledge-based dose estimation that can be utilized by clinicians worldwide to benchmark the quality of their radiotherapy plans.

The ORBIT-RT (Online Real-time Benchmarking Information Technology for RadioTherapy) platform was developed to satisfy four primary design criteria: web-based access, TPS independence, HIPAA compliance, and autonomous operation. ORBIT-RT utilizes MIMCloud™ (MIM Software, Cleveland, OH) to automatically anonymize a user’s DICOM-RT prior to upload and initiate automated processing of the case. From there, ORBIT-RT Java extensions in MIM utilize established knowledge-based dose-volume histogram (DVH) estimation methods to autonomously create DVH estimations for the uploaded DICOM-RT. ORBIT-RT performance is evaluated against a validation set of volumetric modulated arc therapy prostate plans with two key metrics: (i) time to process and display the DVH estimations on the ORBIT-RT platform and (ii) accuracy of the DVH estimations, as quantified by their deviations,

The ORBIT-RT extensions operate quickly (~23 seconds for prostate plans), though the upload, data transfer, and DVH output display extend the entire knowledge-based feedback loop to approximately 3 minutes. ORBIT-RT predictions are consistent with clinical DVHs, showing ˜-0.5±1.0% mean deviation in the 80-105% relative dose interval of the prostate validation set, and comparable estimation accuracy in other regions of the DVH as compared to published predictive models.

ORBIT-RT demonstrated fast and fully-autonomous knowledge-based feedback on a web-based platform that takes only anonymized DICOM-RT as input. The ORBIT-RT system can be used for real-time quality control feedback that provides users with objective comparisons for final plan DVHs.

Funding Support, Disclosures, and Conflict of Interest: K. Moore reports income for personal consulting and speaker honoraria from Varian Medical Systems. This work was supported in part by the Agency for Healthcare Research and Quality (AHRQ R01HS025440).


Treatment Planning, Quality Control, Dose Volume Histograms


TH- External Beam- Photons: Treatment planning using machine learning/Knowledge Based Planning/automation

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