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Quantitative Ultrasound Imaging: From Benchtop to a Clinical Protocol

T Hall1*, J Fowlkes2*, M Averkiou3*, J Mamou4*, I Rosado-Mendez5*, (1) University of WI-Madison/ADCL, Madison, WI, (2) University Michigan Health Systems, Ann Arbor, MI, (3) University of Washington, Seattle, WA, (4) Riverside Research Institute, New York, NY, (5) Universidad Nacional Autonoma de Mexico, Mexico, MX


(Tuesday, 7/14/2020) 3:30 PM - 5:30 PM [Eastern Time (GMT-4)]

Room: Track 1

As Medicine thrives to become more personalized, the need for objective and non-invasive ways to obtain morphological, functional and molecular tissue information is ever more important. Quantitative Ultrasound (QUS) Imaging provides a practical and cost-effective way to obtain this information. Well designed and clear imaging protocols are quintessential for the successful translation of QUS to the clinic.

This symposium will provide an overview of ongoing efforts from the Quantitative Imaging Biomarker Alliance (QIBA) to standardize the clinical application of different QUS techniques. Special emphasis will be placed on the roles that medical physicists have in the process of developing and implementing robust QUS imaging protocols.

The session will be divided in four parts. The first three parts will cover the achievements and present status of the three QIBA ultrasound committees: the shear wave speed committee, the contrast-enhanced ultrasound committee, and the volume blood flow quantification committee. These three parts will describe the advances of each committee, as well as the challenges and clinical findings. The fourth part will provide an overview of QUS biomarkers that are moving towards in clinical implementation, such as acoustic attenuation and backscatter measurements.

Learning Objectives:
1. Describe the physical basis and technical aspects of Quantitative Ultrasound imaging techniques.
2. Understand the challenges of the clinical application of Quantitative Ultrasound Imaging, particularly the importance of considering physical, technical and clinical confounders.
3. Understand the processes followed by QIBA in the design of imaging protocols for QUS-based biomarkers, as well as the role of medical physicists in the successful implementation of the protocols.

Funding Support, Disclosures, and Conflict of Interest: TJH and IRM collaborate with Siemens Healthineers. JBF and MA collaborate with GE Healthcare and Philips Healthcare. MA collaborates with Insighttec. Founded by NIH ( R01HD072077 for TJH; JBF; R21AR074668, R03EB026233, R01CA192407 for JM), RSNA (contract through U. of Wisconsin), and UNAM PAPIIT (IA104518 AND IA102023, IRM)



Quantitative Imaging, Ultrasonics


IM- Ultrasound : Quantitative imaging

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