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Design a Gated and Non-Gated Respiratory Control Auxiliary System for External Beam Radiation Therapy

Jian-Kuen Wu 4, Shih-Han Chen 5, Shu-Hsien Liao 5, Yu-Jen Wang 1,2,3 1 Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei 106, Taiwan, 2 Department of Radiation Oncology, Fu Jen Catholic University Hospital, New Taipei City, Taiwan, 3 School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan, 4 Division of Radiation Oncology, Departments of Oncology, National Taiwan University Hospital, Taipei, Taiwan 5 Institute of Electro-Optical Science and Technology, National Taiwan Normal University, Taipei, Taiwan


(Sunday, 7/14/2019)  

Room: ePoster Forums

Purpose: Respiratory control system becomes a useful therapeutic addition to many patients who received chest or abdomen radiation therapy(RT). Through above techniques, such as active breathing control (ABC), SDX or similar devices, we could reduce treatment volume and may alleviate the radiation toxicity potentially but it may be challenging to check phase and amplitude quality for each patient preciously for different devices.

Methods: We develop a small and portable respiratory monitor system to help these devices to monitor the precise respiratory signal phase. It included two only 2x3x1 cm 6-axis gyroscope detectors will place on patient’s skin (chest and abdomen, respectively). Signals were transmitted by mix Ultra-Wide-Band wireless technique. Home-made software and three different phantoms were built to simulate the respiration wave and heart beats in different clinical scenarios. Clinical patient’s respiratory data were used for validation. Three different scenarios are stepping motor control system for linear accelerator, ceramics piezo driving motor for MR-LINAC, and the modified water-phantom measure system to air-phantom device.

Results: Eight patients who received RT to adrenal area were selected for validation from last five years. We calculated their respiratory waves’ velocity, acceleration /deceleration, pause, and forward/backward. To successful simulate the patients respiratory pattern, the range of X-axis, Z-axis were 1000~2000 mm/min, and Y-axis was 200~ 673 ms/step. It’s sensitive and could simulate all patients pattern properly. One simulation device work well under TureBeamTM system,, one ceramics piezo driving motor (max travel 5cm) with small MR distortion, and one IBA water-phantom measurement system to air- phantom system with less than 1 mm accuracy were all built.

Conclusion: The two six-axis gyroscope detector system with Ultra-Wide-Band wireless technique is very sensitive and precious for respiratory monitor. The three different clinical scenario simulation systems would be very useful to simulate and enhance the accuracy of clinical RT.


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