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Tomographic Thermal Imaging as a Predictor of Skin Reactions in Radiation Therapy

J McCorkindale1*, Y Liao1 , K Jones1 , J Sun2 , A Templeton1 , J Chu1 , J Turian1 , (1) Rush University Medical Center, Chicago, IL, (2) Argonne National Laboratory, Lemont, IL


(Sunday, 7/14/2019) 5:00 PM - 6:00 PM

Room: 221AB

Purpose: An early indicator of radiation induced skin reactions would be a valuable tool for mitigating skin toxicity in radiation therapy patients. Based on previous mouse studies, a tomographic reconstruction of skin effusivity using a flash pulsed thermal imaging system could be used as an early detection system, but translation of the technique to human subjects requires additional development.

Methods: Due to the finite speed of heat propagation, one can calculate the thermal properties of materials at depth based on the decay of surface temperature after impulse heating. A pulsed thermal imaging system has been employed using two flash lamps and an infrared camera. Vinyl tape with measured thermal properties was used as a fiducial and effusivity values of the skin beneath the tape were calculated to a depth of 0.5 mm. Effusivity measurements of known materials were performed to evaluate the accuracy of the system as well as several skin measurements to determine precision.

Results: The thermal effusivity of vinyl tape was first calibrated using the known value of water (1588 W √s/(m² °K)). Calculated values of tape effusivity were found to be 590±7.5 W √s/(m² °K). The effusivity of other materials underlying the vinyl tape were measured as a function of depth by normalizing to the effusivity of the tape. Using this tape calibration value, the effusivity of borosilicate glass was found to be 1370 W √s/(m² °K), which differs <2% from published values. Nine separate measurements of untreated skin of the forearm were made over the course of a week and found to be 1406 W √s/(m2 °K) to a precision of σ=20 W √s/(m² °K).

Conclusion: We have validated the precision and repeatability of the measurement apparatus, allowing detection of effusivity changes which may manifest as a precursor to skin toxicities grade 2 or higher.


Digital Imaging, Heat Transfer, Thermometry


IM- Multi-modality imaging systems: Development (new technology and techniques)

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