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Dosimetric Comparison of Helical Tomotherapy and Intensity-Modulated Radiotherapy for Cervical Cancer Patients with Ovarian-Conserving Radical Surgery

X Liu*, X Lin , Y Yin , Shandong Cancer Hospital Affiliated to Shandong University, Jinan, Shandong


(Sunday, 7/14/2019)  

Room: ePoster Forums

Purpose: To evaluate the dosimetric differences of helical tomotherapy (HT) and intensity-modulated radiotherapy(IMRT)in the treatment of cervical cancer patients with ovarian-conserving radical surgery.

Methods: Twenty patients with cervical cancer were randomly selected. Plans were created using HT and IMRT. The prescription dose was 50 .4Gy/28 fractions .Dosimetric comparison was assessed for doses to targets and organs at risk (bladder, rectum, ovary and femoral heads). Delivery time, monitor units and dosimetric verification results were also compared.

Results: For GTV and PTV,HT had significantly better CI and HI of the target volume than IMRT(p=0.026). HT provided better sparing of the ovary for Dmax and Dmean (p=0.006 and (p=0.040). No differences were seen in the bladder and rectum between techniques. Doses to femoral heads in HT were significantly lower than IMRT(p=0.001) .Delivery time were similar, but HT needed a significantly higher number of MUs than IMRT(7 349±47 vs. 2031±29,P=0.001) .Dose verification results were 98.3 ± 0.8% (HT) vs 94.6 ± 3.2% (VMAT) for global gamma criteria 3%/3 mm .

Conclusion: Although HT had higher number of MUs than IMRT ,HT can obtain better conformity and homogeneity of target volume and better protect the ovary. Therefore, HT deserves to be popularized and applied in cervical cancer patients with ovarian-conserving radical surgery.


Dosimetry, Tomotherapy, Treatment Planning


TH- External beam- photons: tomotherapy

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