Click here to


Are you sure ?

Yes, do it No, cancel

The Role of Double Inversion Recovery Imaging in Acute Ischemic Stroke

NY Choi , S Park , CM Lee , CW Ryu , GH Jahng*, Department of Radiology, Kyung Hee University Hospital at Gangdong, Seoul, Korea


(Sunday, 7/14/2019) 4:30 PM - 5:00 PM

Room: Exhibit Hall | Forum 8

Purpose: To investigate whether double inversion recovery (DIR) imaging can have a role in the evaluation of ischemic brain lesions compared with diffusion-weighted imaging (DWI) and fluid-attenuated inversion recovery (FLAIR) imaging.

Methods: 67 patients within 48 hours of symptom onset underwent MRI scans with FLAIR, DWI with b-value of zero (T2WI) and 1000 s/cm2 (DWI), and DIR sequences. According to the symptom onset times, patients were categorized into four groups: Group I (N=18, onset≤3 hours), Group II (N=15, 3
Results: In Group I to III, Fridman test showed that LNR values were significantly different among the five sequence (p<0.001). LNR values from DWI were significantly different to those from ADC, FLAIR, and T2W, but not DIR (p=0.429) for both groups. Kruskal Wallis test showed that LNR value of only the T2W was significantly different among the four subgroups (p=0.007). LNR values were significantly different between before and after 6 hours onset time groups for DIR (p=0.016), but not for DWI (p=0.051).

Conclusion: For the overall onset times, LNR value of DWI was highest followed by DIR, ADC, FLAIR, and T2W in subgroups. DIR can be helpful in discriminating Group I and II from III and IV. DIR may have an added value to evaluate the ischemic stroke imaging.

Funding Support, Disclosures, and Conflict of Interest: Convergence of Conventional Medicine and Traditional Korean Medicine R&D program funded by the Ministry of Health & Welfare through the Korea Health Industry Development Institute (KHIDI) (HI16C2352, GHJ) and Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2016R1D1A1B03930720, GHJ)


Brain, Diagnostic Radiology, Stroke


IM- MRI : Quantitative Imaging/Analysis

Contact Email