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Beyond Conventional CT Simulation: PET-CT, PET-MR, MR-Only, and Multi-Energy CT

N Tyagi1*, E Graves2*, G El Fakhri3*, A Megibow4*, (1) Memorial Sloan-Kettering Cancer Center, New York, NY, (2) Stanford University, Stanford, CA, (3) Massachusetts General Hospital, Boston, MA, (4) NYU Radiology Associates, New York, NY


(Thursday, 8/2/2018) 10:00 AM - 12:00 PM

Room: Karl Dean Ballroom B1

CT simulation has played an important role in radiation therapy planning and has allowed for greater precision in dose distribution, dose delivery and patient positioning. With increasing use of dose escalation, hypofractionation, adaptive replanning and tighter margins, an accurate assessment of tissue characterization, tumor boundaries and tumor motion range has become even more crucial to achieve therapeutic gain. There have been significant technological advances in anatomical, biological and functional imaging development and applications in recent years, including but not limited to PET, MRI and multi-energy CT. There is great potential for these advances to be used in the radiotherapy clinic to further enhance diagnosis, planning and treatment of various malignancies. As a result, there is keen interest in the medical physics community in learning about novel developments of these new techniques, understanding the principles underlying them, and focusing on applying them and integrating them into the clinic. This session will focus on what is likely to be the next major clinical advancement in the use of advanced multimodality imaging for radiation therapy treatment planning and response assessment. We will summarize the latest developments in MR-only, PET/CT, PET/MR and multi-energy CT and their role and challenges in further enhancing the potential of conventional CT simulation.

Learning Objectives
1. Update on the current and future applications of MR-only for radiotherapy planning
2. Discuss advances in chemistry, biology and physics of PET/CT and their applications in radiation therapy planning
3. Understand development and clinical integration of PET/MR systems and discuss novel applications in diagnosis, therapy and response assessment
4. Describe the clinical advances made in multi-energy CT that can enhance the power of conventional CT



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