Room: Exhibit Hall | Forum 7
Purpose: To compare the differences in the dose-volume histograms between knowledge-based intensity-modulated radiotherapy (K-IMRT) plans and conventional IMRT (C-IMRT) plans of 20 patients with cervical cancer.
Methods: Seventy cervical cancer patients were selected in this study. Sixty cases were selected randomly as a model group. The remaining 10 cases with overlap volume of target and organs at risk (OARs) were categorized as group E1 for open-loop verification. Ten cases from the model group were selected randomly as group E2 for closed-loop verification.
Results: The dose parameters of target in the K-IMRT and C-IMRT plans showed no significant difference. The maximum dose and HI of group E2 had no difference (p > 0.05) in their K-IMRT and C-IMRT plans. The dose parameters in the K-IMRT plans of OARs were superior to those in the C-IMRT plans. For group E1, V20 of the rectum and V15, V20, and V25 of the left and right femoral heads in the K-IMRT plans decreased as compared to those in the C-IMRT plans (p<0.05). For group E2, V25, V30, V35, and D50 of the bladder; V25 and V30 of the rectum; and V15, V20, and V25 of the left and right femoral heads in the K-IMRT plans decreased as compared to those in the C-IMRT plans (p<0.05).
Conclusion: It is feasible to optimize the IMRT plans for cervical cancer patients with the overlap volume of target and OARs using knowledge-based radiation treatmen automatically.
Not Applicable / None Entered.