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Patient Specific Quality Assurance for GammaPod: A Novel Dedicated Breast Stereotactic Radiosurgery Device

S Becker1*, Y Niu2 , Y Mutaf3 , C Yu1,2 , Y Poirier1 , S Feigenberg4 , E Nichols1 , B Yi1 , (1) university of Maryland School Of Medicine, Baltimore, MD, (2) Xcision Medical Systems, Columbia, MD, (3) Boston University Medical Center, Boston, MA, (4) University of Pennsylvania, Philadelphia, Pennsylvania

Presentations

(Wednesday, 8/1/2018) 9:30 AM - 10:00 AM

Room: Exhibit Hall | Forum 4

Purpose: The GammaPod (Xcision Medical System), a novel breast-specific stereotactic radiotherapy device developed at the University of Maryland, has recently completed its first clinical trial and was granted 510k FDA clearance. The GammaPod dynamically dose-paints the target by rotating 36 non-overlapping Co-60 beams while the patient is translated continuously in three longitudinal axes during delivery. From simulation to treatment, the patient’s breast is immobilized using mild negative pressure (150 mmHg) through a device-specific dual cup system with stereotactic fiducials. The cup is secured to both the simulation and treatment tables, functioning as a stereotactic frame. The objective of this study is review the results of the first 17 patients’ PSQA and independent dose calculations used to validate the new technique.

Methods: In the course of clinically implementing Gamma Pod (2016-2017), we developed a patient quality assurance system comprising of point dose ion chamber and film based measurements along with an independent dose calculation algorithm. Measurements are performed using two phantoms: an acrylic phantom, and the patient’s specific breast cups filled with water. For the acrylic phantom, a QA plan recalculated in the phantom is compared to film and ion chamber measurements. For the water-based measurements, the plan is delivered to the patient-specific breast cup filled with water and compared to ion chamber measurements.

Results: For water-based measurements, the mean difference between measured and planned dose or independent calculation was -1.1% ± 1.0 and 8.9% ± 1.8%, respectively. For the acrylic phantom measurements, the mean difference between measured and planned dose or independent calculation was -1.3% ± 0.5% and 4.9% ± 1.6%, respectively. The film mean gamma pass rate (2mm/3%) was 97.9% ± 1.9%.

Conclusion: PSQA for both water and acrylic based measurements have shown that the GammaPod system is able to accurately calculate and deliver the dose to a patient.

Keywords

Breast, Stereotactic Radiosurgery, Quality Assurance

Taxonomy

TH- External beam- photons: extracranial stereotactic/SBRT

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